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  • Overactive and impulsive behaviors are common in TSC and should be monitored in all individuals to ensure early detection and treatment
  • All individuals with overactive and impulsive behaviors should be considered for a clinical diagnostic assessment for ADHD.
  • ADHD in TSC should be treated using the same evidence-based approaches and interventions for the general population, including behavioral supports and pharmacological interventions.
  • When someone has moderate to severe ADHD, treatment with methylphenidate or other stimulant medications should be considered.
  • Even when ADHD is accompanied with epilepsy, intellectual disability, autism, or other physical or TAND manifestations, ADHD symptoms may respond appropriately to treatment.
  • Further research is required to improve the understanding of overactivity, restlessness, and impulsivity in TSC.