Many men with epilepsy will experience changes in sexual drive and performance. For example, many men report a decrease in sex drive and almost one-third of men with epilepsy report difficulty achieving and maintaining an erection, known as erectile dysfunction (ED). In many cases, ED may result as a seizure medication side effect but other medical issues may cause ED. However, this reaction to one medication does not mean you will have the same experience with another. Recurrent uncontrolled seizures may also lead to diminished sex drive and ED. In fact, when seizures are under control, people seem to have improved sexual desire and performance. Men experiencing ED should visit a urologist to get help determining a cause and getting treatment. In addition, men should talk with their neurologist or epileptologist about trying another seizure medication, if possible, in case the ED is a side effect of one medication.
Hormones play an important role in sexual function, and some men with epilepsy have alterations in normal hormone levels. Both seizures and anti-seizure medications can interfere with the way the body uses hormones, resulting in sexual problems. An endocrinologist, or endocrine specialist, may be able to help sort out the complex interactions between hormones, seizures, and medications.