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Kidney (renal) manifestations such as cystic disease and renal angiomyolipomas continue to grow throughout this part of the lifespan. Not only are you/your loved one aging, in which chronic kidney disease tends to manifest in general adulthood, but the progression of TSC-specific manifestations and long-term medication use all contribute to factors that place you or your loved one at risk for chronic kidney disease and/or hypertension. Surveillance with MRI of the abdomen is still recommended every 1 – 3 years during this timeframe. The goal is to be preventative and proactive to decrease progressing to end-stage renal disease, which will be covered later in this section. Ideal diet, daily exercise and maintaining an ideal blood pressure are essential for not only general and cardiovascular health purposes but also to minimize declining renal function.